Hedge Funds Like Royalty Pharma: Should Retail Wear the Crown?
Can Royalty Execute — Or Is It Just High Society? 👑💊
Royalty Pharma plc (NASDAQ: RPRX)
$40.17 | −$0.09 (−0.22%) | As of Jan 9, 2026 – 4:00 PM ET
🎯 FunStock Index™: 7.9 / 10 🎯
Tooltip: A high-quality, cash-generating compounder with a unique moat. Not flashy biotech — more like healthcare’s well-dressed tollbooth operator.
👑 The Royal Setup: What Does Royalty Pharma Actually Do?
Royalty Pharma is not your typical lab-coat biotech burning cash while praying for FDA mercy. Instead, it plays a much calmer — and frankly more aristocratic — game.
The company buys royalties on approved (and near-approved) blockbuster drugs. Think of it as collecting rent on successful medicines without having to invent them, test them, or explain side effects in 45-page disclosures.
Its portfolio spans:
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~35 marketed therapies
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14 development-stage candidates
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Therapeutic areas including oncology, rare disease, neuroscience, immunology, hematology, and diabetes
Founded in 1996 and based in New York, Royalty Pharma has quietly built a diversified, cash-rich healthcare empire that feels more like a hedge fund wearing scrubs.
🎯 Trigger #1: Hedge Funds Like the Stock (A Lot)
When Pat Dorsey shows up, value investors tend to listen.
Royalty Pharma recently became a new holding in Dorsey Asset Management, where it represents ~7.8% of the portfolio — not a nibble, a real bite.
📊 Details:
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Average buy price: ~$36.20
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Position now up roughly +9%
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Q3 2025 addition
Dorsey, one of the original minds behind Morningstar’s economic moat framework, doesn’t chase hype. He looks for durable advantages — and Royalty’s model fits the bill beautifully.
Translation: This isn’t a fling. It’s a long-term relationship.
🏦 Trigger #2: Institutions Are Basically the Court
If institutions are the royal court, Royalty Pharma has a packed ballroom.
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82.3% of shares held by institutions
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90.3% of the float institutionally owned
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782 institutional holders
👑 Top holders include:
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Morgan Stanley (~10%)
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Fidelity (FMR)
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Capital International
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BlackRock
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Baillie Gifford
This level of sponsorship adds liquidity, stability, and credibility. When the market gets choppy, stocks with this kind of backing tend to wobble — not collapse.
🔍 For Royalty Pharma (RPRX)'s Institutional Ownership breakdown, see here.
🐻 Trigger #3: Shorts Are Present… But Not in Control
Short interest sits around 7.1% — respectable skepticism, not outright rebellion.
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Shares short: ~27.7M
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Days to cover: ~7
If sentiment flips more bullish, short covering could add fuel. Not a squeeze setup — but definitely dry tinder.
📈 Trigger #4: Analysts Are Wearing Their Bull Crowns
Wall Street’s tone on RPRX is generally upbeat:
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Consensus: Moderate Buy
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Average price target: ~$45–46
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Upside from current levels: meaningful but not delusional
Recent ratings skew Buy / Strong Buy from firms like TD Cowen, Goldman Sachs, Morgan Stanley, and Citi, with a few cautious Holds sprinkled in for seasoning.
💰 Trigger #5: Earnings That Actually Impress
Royalty Pharma’s Q3 2025 results were quietly excellent:
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Royalty Receipts: +11% YoY
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Portfolio Receipts: $814M (+11%)
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Adjusted EBITDA: +15%
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Operating cash flow: $703M
Management raised full-year 2025 guidance to $3.2–3.25B in portfolio receipts — now expecting 14–16% growth.
Not bad for a business model that doesn’t rely on lab miracles.
Add to that:
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Aggressive share buybacks
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Long-dated debt with a ~3.75% weighted average cost
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Strong liquidity
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Expanding royalty portfolio (Amgen, Alnylam, Roche-related assets)
This is boring done beautifully — and boring often wins.
🧠 Bonus insight: In 2025, Royalty Pharma partnered with Deloitte on a landmark report about the biopharma royalty market, highlighting royalties as a non-dilutive, scalable funding engine for life sciences innovation. One sentence takeaway: this market is growing, institutionalizing, and maturing fast.
👉 Want the full picture? Dive into Royalty Pharma (RPRX)'s financials here.
🍬 Trigger #6: No Insider Buys — But Massive Buybacks
While insiders haven’t been buying aggressively, the company itself is.
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$3B authorized buyback program
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~$1.2B already deployed in 2025
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Share count shrinking nicely
That’s shareholder candy 🍬 — and a strong vote of confidence from management.
🚀 Trigger #7: Momentum Awakens
RPRX is still about 29% below its all-time high (set shortly after its IPO in 2020), yet momentum has improved and fundamentals look stronger than ever.
Sometimes the crown just needed polishing.
🧮 Valuation Snapshot: Expensive… or Elegant?
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Forward P/E: ~12
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Dividend yield: ~2.3%
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Cash flow: strong and recurring
Yes, price-to-sales looks rich — but that’s typical for high-margin, royalty-based cash machines.
This isn’t a pharma lottery ticket. It’s a cash compounding vehicle.
🏁 Quick Take / TL;DR ⚡
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👑 Unique royalty-based biopharma model
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💰 Strong cash flows and growing dividends
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🏦 Heavy institutional backing
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🔄 Aggressive share buybacks
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📈 Analysts generally bullish
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⚖️ Valuation reasonable on forward earnings
Royalty Pharma offers a rare blend of income, stability, and exposure to biotech innovation — without biotech-level stress.
❓ FAQ
Is Royalty Pharma a biotech company?
Not really. It doesn’t develop drugs — it finances and collects royalties from them.
Does RPRX pay dividends?
Yes. The dividend yield is ~2.3%, with a shareholder-friendly track record.
What’s the main risk?
Slower-than-expected drug sales in its royalty portfolio, regulatory shocks, or broader biotech sentiment turning sour.
Is this a growth stock or income stock?
Both. Think income-first with growth seasoning.
💡💡💡 Curious about another deep oil exploration play?
Check our take on UnitedHealth Group.
✍️ About the Author
Frédéric Marsanne is the founder of FUNanc1al — part market analyst, part storyteller, part accidental comedian. A longtime investor, entrepreneur, and venture-builder across tech, biotech, and fintech, he blends sharp insights with humor to help readers laugh, learn, live better lives, and invest a little wiser. When not decoding insider buys or poking fun at earnings calls, he’s building Cl1Q, writing fiction, painting, or discovering new passions to FUNalize.
🧾⚠️📢 Fun(anc1al) but Serious Disclaimer: 🧾⚠️📢
This article is for informational and entertainment purposes only and does not constitute investment advice. Markets can be irrational, biopharma can be volatile, and even royalty checks can bounce. You may like your portfolio royal with cheese, but always DYOR, resist FOMO, and never invest money you can’t afford to lose. 🧀👑
We laugh, we analyze, we meme.
We’re FUNancial advisors — not financial advisors. 😄📉📈
Consult a qualified financial professional if you must.
Invest at your own risk. Love at any pace. Laugh at every turn. 😄
Be Happy. 😄😄
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